Published Research

Welcome to our comprehensive collection of published research on fetal heart development and health. Explore the latest findings, breakthroughs, and insights into the intricacies of fetal cardiac physiology. Our curated selection encompasses studies spanning prenatal diagnosis, congenital heart defects, fetal echocardiography, and advancements in fetal cardiology interventions. Delve into the forefront of scientific discovery as we unravel the mysteries of fetal heart development, with implications for prenatal care, maternal health, and pediatric cardiology. Whether you're a healthcare professional, researcher, or parent-to-be seeking knowledge, our repository offers a valuable resource to deepen understanding and drive innovation in fetal cardiovascular medicine.

Fetal Heart Society Researchers Show Disparities in Prenatal Detection of TGA

PI: Dr. Krishnan
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HLHS Prenatal

Associations Between Maternal Sociodemographics and Hospital Mortality in Newborns With Prenatally Diagnosed Hypoplastic Left Heart Syndrome is the title of this published research.
Please review the manuscript HERE.

FHS Statement on Dobbs vs. Jackson

With the recent ruling of the US Supreme Court in the matter of Dobbs vs. Jackson, leaders from within the Fetal Heart Society community submitted a Letter to the Editor that was recently published in Ultrasound in Obstetrics & Gynecology. The letter discusses the implications of this decision from the perspective of physicians that care for critically ill fetuses and their families.
Please review the manuscript HERE.

Three FHS Abstracts Accepted to ASE 2022

The Fetal Heart Society was well represented at the ASE 2022 (Hybrid) conference. Congratulations to Kelly Cox, Jennifer Cohen, Anita Moon-Grady and all of their study group members for their great achievements.
Please read the accepted abstract summaries HERE.

Manuscript and Podcast: Current State of Fetal Heart Disease Counseling and Training

Fetal Heart Society researchers have published a manuscript on Counseling for patients with Fetal Heart Disease. In addition to publication in Pediatric Cardiology, the work was also featured in the PediHeart podcast with an interview of first author, Dr. Jenna Keelan. See below for links to the manuscript and the podcast. Congratulations to all who contributed to this important work!

Also, stay tuned for additional efforts by the Fetal Heart Society to promote some of the improvements discussed below.
PubMed link
PediHeart Podcast #204

Fetal Heart Society Researchers Show Disparities in Prenatal Detection of TGA

PI: Mary Donofrio
Stage: STUDY PUBLISHED
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Updated Statement on Echo Services and COVID-19

The ASE released a statement on Adapting Services to Evolving COVID-19 Pandemic.
Please review their statement HERE.

The Fetal Heart Society: Facilitating Multidisciplinary Collaborative Fetal Cardiovascular Research

Authors: Alfred Abuhamad, Mary T. Donofrio * and On behalf of the Fetal Heart Society Governing Board and Steering Committee

WHAT’S ALREADY KNOWN ABOUT THIS TOPIC?
• Fetal cardiology is a highly specialized field that crosses multiple
disciplines. In order to expand knowledge and discovery, a
structured organization which fosters multidisciplinary research
collaboration across institutions is needed.

WHAT DOES THIS STUDY ADD?
• The newly formed Fetal Heart Society is a non-profit multidisciplinary
research organization with an overarching goal of advancing the
field of fetal cardiovascular care and science through collaborative
research, education, and mentorship.

View published article

More Fetal Heart Society Publications

Congenitally Corrected Transposition of the Great Arteries: Fetal Diagnosis, Associations, and Postnatal Outcome: A Fetal Heart Society Research Collaborative Study. Cohen J, Arya B, Caplan R, Donofrio MT, Ferdman D, Harrington JK, Ho DY, Hogan W, Hornberger LK, Jhaveri S, Killen SAS, Lindblade CL, Michelfelder E, Moon-Grady AJ, Patel S, Quezada E, Ronai C, Sanchez Mejia AA, Schidlow DN, Stiver C, Thakur V, Srivastava S.J Am Heart Assoc. 2023 Jun 6;12(11):e029706. doi: 10.1161/JAHA.122.029706.

Associations Between Maternal Sociodemographics and Hospital Mortality in Newborns With Prenatally Diagnosed Hypoplastic Left Heart Syndrome. Lopez KN, Morris SA, Krishnan A, Jacobs MB, Bhat AH, Chelliah A, Chiu JS, Cuneo BF, Freire G, Hornberger LK, Howley L, Husain N, Ikemba C, Kavanaugh-McHugh A, Kutty S, Lee C, McBrien A, Michelfelder EC, Pinto NM, Schwartz R, Stern KWD, Taylor C, Thakur V, Tworetzky W, Wittlieb-Weber C, Woldu K, Donofrio MT, Peyvandi S; Fetal Heart Society Research Collaborative.Circulation. 2023 Jul 18;148(3):283-285. doi: 10.1161/CIRCULATIONAHA.123.064476.

Fetal Echocardiographic Z Score Pilot Project: Study Design and Impact of Gestational Age and Variable Type on Reproducibility of Measurements Within and Across Investigators. Moon-Grady AJ, Lee H, Lopez L, Fatusin O, Freud LR, Hogan W, Krishnan A, McFarland C, Minich LL, Morris SA, Pinto N, Presson AP, Tacy TA, Donofrio MT; Fetal Heart Society.J Am Soc Echocardiogr. 2023 Sep;36(9):978-997. doi: 10.1016/j.echo.2023.05.010. Epub 2023 Jun 9.

Reviews and Commentaries

Multidisciplinary Collaboration in Fetal Cardiovascular Research: The Time Has Come. [pubmed.ncbi.nlm.nih.gov] Donofrio MT, Rychik J; Fetal Heart Society Governing Board and Steering Committee.J Am Soc Echocardiogr. 2016 Feb;29(2):140-2. doi: 10.1016/j.echo.2015.11.012. Epub 2015 Dec 19. PMID: 26711365 No abstract available.

The Fetal Heart Society: facilitating multidisciplinary collaborative fetal cardiovascular research. [pubmed.ncbi.nlm.nih.gov] Abuhamad A, Donofrio MT; Fetal Heart Society Governing Board and Steering Committee. Prenat Diagn. 2016 May;36(5):489-91. doi: 10.1002/pd.4794. Epub 2016 Mar 29. PMID: 26918283 No abstract available.

Specific Considerations for Pediatric, Fetal, and Congenital Heart Disease Patients and Echocardiography Service Providers during the 2019 Novel Coronavirus Outbreak: Council on Pediatric and Congenital Heart Disease Supplement to the Statement of the American Society of Echocardiography: Endorsed by the Society of Pediatric Echocardiography and the Fetal Heart Society. [pubmed.ncbi.nlm.nih.gov]Barker PCA, Lewin MB, Donofrio MT, Altman CA, Ensing GJ, Arya B, Swaminathan M.J Am Soc Echocardiogr. 2020 Jun;33(6):658-665. doi: 10.1016/j.echo.2020.04.005. Epub 2020 Apr 9. PMID: 32503702 Free PMC article. Review. No abstract available.

Prenatal cardiac care: Goals, priorities & gaps in knowledge in fetal cardiovascular disease: Perspectives of the Fetal Heart Society. [pubmed.ncbi.nlm.nih.gov] Pinto NM, Morris SA, Moon-Grady AJ, Donofrio MT. Prog Pediatr Cardiol. 2020 Dec;59:101312. doi: 10.1016/j.ppedcard.2020.101312. Epub 2020 Oct 17. PMID: 33100800 Free PMC article.

ASE Statement on Adapting Pediatric, Fetal, and Congenital Heart Disease Echocardiographic Services to the Evolving COVID-19 Pandemic. [pubmed.ncbi.nlm.nih.gov]Altman CA, Donofrio MT, Arya B, Wasserman M, Ensing GJ, Cohen MS, Lewin MB, Swaminathan M, Barker PCA.J Am Soc Echocardiogr. 2021 May;34(5):553-561. doi: 10.1016/j.echo.2021.01.012. Epub 2021 Jan 28. PMID: 33516940 Free PMC article.

Implications of United States Supreme Court's ruling on Dobbs vs Jackson Women's Health Organization: perspective of physicians caring for critically ill fetuses and newborns. [pubmed.ncbi.nlm.nih.gov] Arya B, Donofrio MT, Freud LR, Hornberger LK, Moon-Grady AJ, Morris SA, Pinto N, Simpson LL, Cuneo BF, Divanovic A, Jaeggi E, Peyvandi S, Puchalski MD, Rychik J, Schidlow DN, Srivastava S, Tacy TA, Tworetzky W, Walsh MJ. Ultrasound Obstet Gynecol. 2022 Dec;60(6):812-813. doi: 10.1002/uog.26107. Epub 2022 Nov 10.

Publications Endorsed by the Fetal Heart Society

Care of the Fetus With Congenital Cardiovascular Disease: From Diagnosis to Delivery. [pubmed.ncbi.nlm.nih.gov] Haxel CS, Johnson JN, Hintz S, Renno MS, Ruano R, Zyblewski SC, Glickstein J, Donofrio MT. Pediatrics. 2022 Nov 1;150(Suppl 2):e2022056415C. doi: 10.1542/peds.2022-056415C.